Avanafil Information
What is this drug used for?
• It is used to treat erectile dysfunction (ED).
• It may be given to you for other reasons. Talk with the doctor.
Possible side effects
Avanafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
• Flushing.
• Headache.
• Sore throat.
• Back pain.
• Stuffy nose.
• Runny nose.
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Chest pain or pressure or a fast heartbeat.
• A heartbeat that does not feel normal.
• Very bad dizziness or passing out.
• Very bad headache.
• Very upset stomach or throwing up.
• Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
• Change in eyesight, eye pain, or very bad eye irritation.
• Loss of eyesight.
• Change in hearing.
• Hearing loss.
• Ringing in ears.
• Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. This may happen even when you are not having sex. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex.
Medication Safety Issues
Sound-alike/look-alike issues:
Avanafil may be confused with sildenafil, tadalafil, vardenafil
Storage/Stability
Store at 20°C to 25°C (68°F to 77°F); excursions are permitted to 30°C (86°F). Protect from light.
Adverse Reactions
>10%: Central nervous system: Headache (1% to 12%)
2% to 10%:
Cardiovascular: Flushing (3% to 10%), ECG abnormality (1% to 3%)
Central nervous system: Dizziness (1% to 2%)
Gastrointestinal: Viral gastroenteritis (≤2%)
Neuromuscular & skeletal: Back pain (1% to 3%)
Respiratory: Nasopharyngitis (1% to 5%), nasal congestion (1% to 3%), upper respiratory tract infection (1% to 3%)
<2%, postmarketing, and/or case reports: Abdominal distress, angina pectoris, anterior ischemic optic neuropathy (nonarteritic), arthralgia, balanitis, bronchitis, constipation, cough, deep vein thrombosis, depression, diarrhea, drowsiness, dyspepsia, dyspnea on exertion, epistaxis, fatigue, gastritis, gastroesophageal reflux disease, hearing loss, hematuria, hyperglycemia, hypertension, hypoglycemia, hypotension, increased serum ALT, influenza, insomnia, limb pain, muscle spasm, musculoskeletal pain, myalgia, nausea, nephrolithiasis, oropharyngeal pain, palpitations, peripheral edema, pollakiuria, priapism, pruritus, sinus congestion, sinusitis, skin rash, tinnitus, urinary tract infection, vertigo, vision color changes, vision loss (temporary or permanent), vomiting, wheezing
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